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Naloxone

Naloxone: An opioid receptor antagonist that rapidly binds to opioid receptors, blocking heroin from activating them. An appropriate dose of naloxone acts in less than 2 minutes and completely eliminates all signs of opioid intoxication to reverse an opioid overdose.[1]

Naloxone that can be used by nonmedical personnel has been shown to be cost-effective and save lives.  In April 2014, the U.S. Food and Drug Administration (FDA) approved a Naloxone hand-held auto-injector called Evzio, which rapidly delivers a single dose of naloxone into the muscle or under the skin, buying time until medical assistance can arrive.[2] 

Law enforcement officers are often the first responders in overdose cases as a result many law enforcement agencies are training officers to administer naloxone.[3] 

 


[1] Source:  National Institute of Drug Abuse (NIDA).  Research Report Series:  Heroin. November 2014, Bethesda, MD:  National Institute of Drug Abuse (NIDA). 

[2] Source:  National Institute of Drug Abuse (NIDA).  Research Report Series:  Heroin. November 2014, Bethesda, MD:  National Institute of Drug Abuse (NIDA). 

[3] (U) U.S. Department of Justice, Drug Enforcement Administration, DEA Intelligence Report, National Heroin Threat Assessment Summary; April 2015